Radial growth rate

Automation with the Reshape Microbiology Platform

The Reshape platform addresses key challenges faced by scientists:

1. High Throughput Analysis: Facilitating the simultaneous study of multiple strains and factors, enhancing efficiency and accelerating time to market.
2. Versatility in Assay Design: Adaptable to a wide variety of factors for efficient design of experiments, serving diverse research needs while obtaining info on both growth rates and time of appearance
3. Precision and Reproducibility: Ensuring accurate and consistent results while minimizing human error and enabling reproduction easily in different teams.
4. Integration with Existing Systems: Easing workflow and data management, consolidating results into a single platform.
5. Empowering Scientists and R&D Managers: Reducing manual labor, expediting decision-making, and fostering innovation.

Applications of Radial Growth Assays

Radial growth assays have extensive applications:

1. Inhibitory Effects: Critical for testing anti-fungal agents and developing preservation strategies in a wide range of industries such as food and cosmetics
2. Optimization of Growth Media: Essential for tailoring growth conditions within a wide range of factors
3. Pharmaceuticals: Instrumental in developing anti-fungal treatments and optimizing performance of fungicides
4. Agriculture: Vital in studying crop diseases and soil health as fungal pathogens are one of the biggest threats to crops around the world
5. Industrial Processes: Key for optimizing fermentation and bioprocessing and understanding morphologies in different conditions

Showcase: Effects of NaCl on Radial Growth

Objective:

Investigate the impact of different NaCl concentrations on 3 fungal strains growing on PDA (24g/L of Neogen PDA media).

Method:

1. Prepare media with varying NaCl concentrations and pin-inoculate fungal spores onto each plate in triplicate
2. Utilize the Reshape platform's advanced imaging to capture growth at high time resolution, transforming a traditionally labor-intensive, error-prone task into a streamlined, precise process which can be executed at high throughput
3. Analyze and post-process data to build a precise model of the impact of salt concentration on fungal growth rates, showcasing the platform's capability for complex analysis.

‍

Results:

Benefits:

• Efficiency for Scientists and lab technicians: Minimizes manual work, freeing time for more impactful tasks
• Informed Decision Making for R&D Managers: Predictable results and lower project target risks enhances commercial outcomes
• Scalability: Adaptable to a range of study scales and number of factors - even suitable for downscaling for very high throughput applications.

Conclusion

The Reshape Microbiology Platform brings a modern approach to radial growth assays for fungi, enabling high-throughput automation and precise data analysis. It opens up avenues for innovation across food preservation, pharmaceuticals, agriculture, and beyond.

‍

LIMS Integration and Further Support

• Barcode reading capabilities for sample tracking.
• Direct integration with your existing LIMS system.
• Continuous support from our data science team for custom-built solutions and monitoring of hard-to-assess organisms

‍